Pharmaceutical compositions containing biodegradable polymers
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United States of America Patent
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May 29, 1984
Grant Date -
N/A
app pub date -
Nov 23, 1981
filing date -
Nov 29, 1980
priority date (Note) -
Expired
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Abstract
Polymers formed by incomplete esterification of the hydroxy groups of a water-soluble polymer such as polyvinyl alcohol, amylose or dextran with a pharmacologically acceptable mono- or di-carboxylic acid to an extent sufficient to render the polymer water-insoluble although still water-swellable, are biodegradable. They are useful for the formulation of pharmaceutical compositions for parenteral administration, particularly in the form of injectable fine particles in which a drug is intimately mixed with or encapsulated by the polymer.
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