Magnetic iron-dextran microspheres

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United States of America Patent

PATENT NO 4452773
SERIAL NO

06365562

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Abstract

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The invention relates to colloidal sized particles composed of magnetic iron oxide (Fe.sub.3 O.sub.4) coated with a polysaccharide, preferably dextran, or a derivative thereof having pendant functional groups. The particles have a magnetic moment, are electron dense, and are stable and non-aggregating under physiological conditions. They can be covalently bonded to antibodies, enzymes and other biological molecules and used to label and separate cells, cellular membranes and other biological particles and molecules by means of a magnetic field.

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Patent Owner(s)

Patent OwnerAddress
BRITISH COLUMBIA UNIVERSITY OFUNIVERSITY-INDUSTRY LIASON OFFICE IRC ROOM 331 HEALTH SCIENCES MALL VANCOUVER BRITISH COLUMBIA V6T 1Z3

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Molday, Robert S Vancouver, CA 5 554

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