Antihemophilic factor concentrate
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United States of America Patent
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-
Jun 19, 1984
Issued Date -
N/A
app pub date -
Sep 29, 1982
filing date -
Feb 26, 1980
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel antihemophilic factor concentrates and process for making the same are disclosed. An aqueous solution of anithemophilic factor proteins is obtained, preferably by solubilizing antihemophilic factor proteins from blood plasma cryoprecipitate in water. The aqueous solution is purified to remove unwanted protein, for example, by mixing the aqueous solution with aluminum hydroxide. Then, the aqueous solution is ultrafiltered to concentrate it, mixed with buffer and saline and adjusted to an acid pH, and freeze-dried.
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