Prevention of analgesic abuse
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United States of America Patent
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Jul 3, 1984
Issued Date -
N/A
app pub date -
Dec 11, 1981
filing date -
Jan 24, 1980
priority date (Note) -
Expired
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Abstract
This invention concerns a method for decreasing both the oral and parenteral abuse potential of strong analgetic agents such as oxycodone, propoxyphene and pentazocine by combining an analgesic dose of the analgetic agents with naloxone in specific, relatively narrow ranges. Oxycodone-naloxone compositions having a ratio of 2.5-5:1 parts by weight and pentazocine-naloxone compositions having a ratio of 16-50:1 parts by weight are preferred.
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