Importance

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Abstract

For the controlled cooling of specimens which are at least partially of liquid form, especially biological specimens, it is important that crystallization at the freezing point takes place locally, without supercooling, and preferably with absorption of the latent heat of fusion. At a temperature which is a predetermined amount above a given critical temperature for the specimen, e.g. its freezing point, a Peltier effect module is energized to effect supplementary cooling at a local area, for example one end of the specimen. The Peltier effect module and the specimen in its container supported in a sample holder are relatively movable. Preferably, the module is displaced, this being initiated by the insertion and removal of the sample holder, preferably by direct mechanical engagement.

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First Claim