7,6 Dioxo-4H,6H-pyrano[3,2-g]quinoline dicarboxylic acids and anti-allergic use thereof

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United States of America Patent

PATENT NO 4474787
SERIAL NO

06344982

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Abstract

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There are described compounds of formula I ##STR1## in which an adjacent pair of R.sub.5, R.sub.6, R.sub.7 and R.sub.8 form a chain --COCH.dbd.CE--O--, and the remainder of R.sub.5, R.sub.6, R.sub.7 and R.sub.8, which may be the same or different, each represent hydrogen, hydroxy, alkyl, halogen, alkenyl, alkoxy, or --NR.sub.1 R.sub.2 in which R.sub.1 and R.sub.2, which are the same or different, are each hydrogen or alkyl, Rg is hydrogen, alkyl, alkenyl or phenyl-alkyl, and E is --COOH, a 5-tetrazolyl group or an (N-tetrazol-5-yl) carboxamido group, and pharmaceutically acceptable derivatives thereof. There are also described processes for making the compounds and pharmaceutical, e.g. anti-allergic, compositions containing the compounds.

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Patent Owner(s)

Patent OwnerAddress
KING PHARMACEUTICALS INC501 5TH STREET BRISTOL TN 37620

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cairns, Hugh Loughborough, GB2 9 62
Cox, David Loughborough, GB2 154 3097

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