Process of treating inflammation with human urinary thiol protease inhibitor

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United States of America Patent

PATENT NO 4479937
SERIAL NO

06524549

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Abstract

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An anti-inflammatory agent comprising as an active component an inhibitor specifically inhibiting a thiol protease, which is obtained from human urine by extraction and purification. This agent has an action of inhibiting a disease caused by a thiol protease. This anti-inflammatory agent is prepared by a process in which a thiol protease inhibitor is extracted and purified from human urine by adopting in combination at least two treatments selected from a treatment with a molecular filter, a treatment with an ion exchanger, a treatment with an adsorber and an affinity chromatographic treatment.

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Patent Owner(s)

Patent OwnerAddress
ZERIA SHINYAKU KOGYO KABUSHIKI KAISHA A COMPANY OF JAPANNO 10-11 NIHONBASHI KOFUNECHO CHUO-KY TOKYO-TO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hiratani, Hajime Osaka, JP 19 291
Sasaki, Koji Omiya, JP 229 1819
Sato, Hiroshi Toda, JP 974 10580
Takagi, Kaname Tama, JP 4 11
Yuki, Yoshikazu Kobe, JP 16 45

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