2-Amino-5-aminomethyl-2-oxazolines, compositions and use

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United States of America Patent

PATENT NO 4497812
SERIAL NO

06539286

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Abstract

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This invention relates to new 2-amino-5-aminomethyl-2-oxazolines, the method of preparing them, and their pharmacological properties making possible their application in cardiovascular, psychotropic, antiinflammatory antiallergic, antihistamine, antiH.sub.2 therapy. These new products have the general formula: ##STR1## wherein R.sub.1 and R.sub.2 independently represent an alkyl radical of C.sub.1 to C.sub.4, or a carbocyclic alkyl radical having less than 4 rings, or a carbocyclic radical having less than 4 rings; R.sub.1 and R.sub.2 can form, with the nitrogen atom to which they are attached, a 4 to 7 member heterocycle containing 1 or 2 nitrogen atoms, and either 1 or 0 oxygen atoms. This heterocycle can be substituted by R with R being a lower alkyl, allyl, benzyl, pyridyl, phenyl substituted or not by one or more substituents such as halogen, trifluoromethyl, methyl, methoxy, hydroxy.

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Patent Owner(s)

Patent OwnerAddress
SOCIETE CORTIAL S A7 RUE DE 1'ARMORIQUE PARIS 75015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Creuzet, Marie-Helene Bordeaux, FR 13 53
Feniou, Claude Pessac, FR 17 61
Jarry, Christian Artigues pres Bordeaux, FR 6 18
Pontagnier, Henri Pessac, FR 15 68
Prat, Gisele Talence, FR 15 71

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