N-(5-aminomethyl-2-oxazolin-2-yl)-N'-phenylureas, compositions and use

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United States of America Patent

PATENT NO 4499090
SERIAL NO

06539285

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Abstract

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This invention relates to new N-(5-aminomethyl-2-oxazoline-2-yl)-N'-phenylureas, the method for producing them and their application in therapy, particularly in treating convulsions, rhythm troubles, ulcerous disorders or inflammatory or edematous conditions. The products of this invention have the general formula: ##STR1## wherein R.sub.1 and R.sub.2 independently represent an alkyl radical of C.sub.1 to C.sub.4, or a carbocyclic alkyl radical having 3 or less rings, or a carbocyclic radical having 3 or less rings; R.sub.1 and R.sub.2 can form, with the nitrogen atom to which they are attached, a 4 to 7 member heterocycle containing 1 or 2 nitrogen atoms and 1 or 0 oxygen atoms, said heterocycle can be substituted by R with R being an alkyl radical of C.sub.1 to C.sub.4, allyl, benzyl, pyridyl, phenyl substituted or not by one or more substituents such as halogen, trihalomethyl, alkyl of C.sub.1 to C.sub.4, hydroxy, or alkoxy having a C.sub.1 to C.sub.4 alkyl radical.

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Patent Owner(s)

Patent OwnerAddress
SOCIETE CORTIAL S A7 RUE DE 1'ARMORIQUE PARIS 75015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Creuzet, Marie-Helene Bordeaux, FR 13 53
Feniou, Claude Pessac, FR 17 61
Jarry, Christian Artigues Pres Bordeaux, FR 6 18
Pontagnier, Henri Pessac, FR 15 68
Prat, Gisele Talence, FR 15 71

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