Particle reagent size distribution measurements for immunoassay
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United States of America Patent
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Jun 4, 1985
Grant Date -
N/A
app pub date -
Mar 11, 1983
filing date -
Mar 11, 1983
priority date (Note) -
Expired
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Abstract
A highly sensitive and rapid method for quantitatively assaying analytes in liquid media by directly measuring changes in particle size distribution of reagent particles having analyte insolubilized thereon in a system undergoing antibody-induced aggregation has been developed. The amount of analyte initially present can be determined by measuring the change in the distribution of particle size with time, the concentration of a particular size particle at a given time, the rate of formation of a particular size particle, or the steady-state maximum concentration for a particular size particle.
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