Constant release rate solid oral dosage formulations of propranolol
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United States of America Patent
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Jun 11, 1985
Issued Date -
N/A
app pub date -
Feb 16, 1984
filing date -
Jan 3, 1983
priority date (Note) -
Expired
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Abstract
A constant order release rate solid oral dosage formulation of propranolol or a pharmaceutically acceptable salt thereof, said formulation comprising: a therapeutically effective amount of propranolol or a pharmaceutically acceptable salt; from about 0.5 to 6.0 weight percent of an acid-retardant or hydrophobic cellulose derivative; from about 2.5 to 35 weight percent of a hydrogenated vegetable oil: from about 1 to 20 weight percent of an acrylic acid polymer; from about 0.5 to 4.0 weight percent of fumed silicon dioxide and from about 0.4 to 3.0 percent of a lubricant.
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