Dioxy hexahydrobenzo[6,7]cyclohepta[1,2,3-de]isoquinoline derivatives useful as neuroleptic agents
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United States of America Patent
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Jun 11, 1985
Grant Date -
N/A
app pub date -
Jun 13, 1983
filing date -
Jun 13, 1983
priority date (Note) -
Expired
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Abstract
1,2,3,7,8,12b-Hexahydrobenzo[6,7]cyclohepta[1,2,3-de]isoquinoline derivatives, characterized by having two adjacent oxy substituents at positions 4 and 5 or at positions 5 and 6, are disclosed. Thus, the substituent at position 5 is lower alkoxy or hydroxy and the substituents at positions 4 and 6 are different and are hydrogen or hydroxy. The derivatives are neuroleptic agents, free of extrapyramidal side effects. Methods for the preparation and for the use of the derivatives also are disclosed.
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