Tricyclic derivatives of 5,6-dihydro-11H-dibenzo (b,e) azepin-6-one having pharmacological activity

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United States of America Patent

PATENT NO 4551451
SERIAL NO

06639687

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Abstract

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A pharmacologically active compound has the general formula ##STR1## in which R is a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; R.sub.1 and R.sub.2, which can be different, represent a hydrogen atom, a hydroxyl group, an alkyl group, an alkoxy group, an arylalkyl group, or an arylalkoxy group, or can jointly represent an oxygen atom or a CHCOOR.sub.1 ' group where R.sub.1 ' is a hydrogen atom or an alkyl group; and R.sub.3 represents a hydrogen or halogen atom or an alkyl, NH.sub.2, NO.sub.2, NHCO-alkyl, NHCO-aryl, NHCONH-alkyl or NHCOHN-aryl group. These compounds act on the central nervous system and have an anti-convulsant sedative activity.

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Patent Owner(s)

Patent OwnerAddress
A MENARINI S A SI-50131 FIRENZE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Furio, Martino Rome, IT 1 1
Ghelardoni, Mario Florence, IT 9 29
Giolitti, Alessandro Florence, IT 8 18
Meli, Alberto Florence, IT 11 35
Pestellini, Vittorio Florence, IT 13 35
Volterra, Giovanna Florence, IT 5 11

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