Vaccine compositions
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United States of America Patent
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-
Feb 4, 1986
Grant Date -
N/A
app pub date -
Jun 9, 1981
filing date -
Jun 9, 1981
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention describes the inactivation of target cells by treatment of said cells with psoralens and irradiation with long wave length ultraviolet light. The inactivated cells are shown to be antigenic and are shown to be non-infective. These cells are useful as target antigens for in vitro assays of cellular immunity. Diagnostic kits containing the inactivated, target cells are prepared for use in serologic assays. Since the inactivated cells are immunogenic and non-infective, they are also useful as vaccines.
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