Solid pharmaceutical compositions comprising MSM and their production
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United States of America Patent
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-
Feb 4, 1986
Issued Date -
N/A
app pub date -
Feb 28, 1984
filing date -
Aug 30, 1979
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Methylsulfonylmethane (MSM) is useful as a tableting and granulating aid for pharmaceutically active agents, especially those which are unstable in the presence of moisture, mixtures therewith being or formable into free-flowing powders or granules which are readily compressible into tablets of improved properties. A preferred method of forming such powders or granules involves mixing the pharmaceutically active agent under substantially anhydrous conditions with molten MSM or with particulate solid MSM at its softening point, cooling the resultant mixture and, when the MSM was molten, forming the solidified melt into granules or a free flowing powder and thereafter, if desired, compressing the powder or granules into tablets.
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