Process for the preparation of a biologically active extract
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United States of America Patent
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-
Mar 18, 1986
Grant Date -
N/A
app pub date -
Sep 19, 1984
filing date -
Oct 5, 1983
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A mammal organ, for example the thymus, or a cell culture is comminuted to form a slurry, accompanied by cell disintegration, high molecular weight substances are precipitated by heating and removed by centrifuging, and residual substances of molecular weight greater than 10,000 are separated out by ultrafiltration; finally, the salts are substantially removed by electrodialysis. A biologically active, low-salt, sterile, pyrogen-free and antigen-free complete extract is obtained and, in contrast to all known processes, no foreign substance or auxiliary, other than water--not even a preservative or a carrier for separation methods--is used.
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