Pharmaceutical compositions containing insulin
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United States of America Patent
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-
Apr 1, 1986
Grant Date -
N/A
app pub date -
May 9, 1984
filing date -
May 23, 1983
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The invention provides a pharmaceutical composition for the oral administration of insulin comprising insulin, a bile acid or alkali metal salt thereof, the bile acid being selected from the group consisting of cholic acid, chenodeoxycholic acid, taurocholic acid, taurochenodeoxycholic acid, glycocholic acid, glycochenocholic acid, 3.beta.-hydroxy-12-ketocholic acid, 12.alpha.-3.beta.-dihydrocholic acid, and ursodesoxycholic acid, and a protease inhibitor, the composition being provided with an enterocoating to assure passage through the stomach and release in the intestine.
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