Treatment of negative symptoms of schizophrenia

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United States of America Patent

PATENT NO 4588721
SERIAL NO

06674616

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Therapeutic process for treating the negative symptoms of schizophrenia in humans comprising the systematic administration of a compound of the formula ##STR1## X is a member selected from the group consisting of --H, --CH.sub.3, and --CH.sub.2 --O--R; wherein R is hydrogen, alkyl of from 1 to 3 carbon atoms, inclusive, ##STR2## wherein n is 0 to 16, inclusive, and m is 1 to 16 inclusive; Y is hydrogen or, provided when Z is hydrogen and X is CH.sub.3, hydroxy; Z is hydrogen or, provided when Y is hydrogen and X is --CH.sub.3, chloro; including the N-oxides and pharmacologically acceptable acid addition salts thereof in combination with a pharmaceutical carrier.

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Patent Owner(s)

Patent OwnerAddress
UPJOHN COMPANY THE KALAMAZOO MICHIGAN A CORP OF DELAWARENot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mahan, Donald R San Jose, CA 1 54

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