Process for the production of cell stimulating agents

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United States of America Patent

PATENT NO 4599176
SERIAL NO

06495956

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention concerns a process for obtaining cell respiratory stimulating active agents having a molecular weight in the range of about 300 to 8000 Dalton, by defibrination of calves blood, hemolyzing the solution obtained thereby, separating the proteins and substances having a molecular weight of over about 8000 Dalton comprised in the hemolyzed solution by a membrane separation procedure, concentrating the resulting protein- and high molecular weight-freed solution under reduced pressure at a temperature not exceeding 40.degree. C. to a density in the range of 1.10 to 1.15 g/ml at 20.degree. C. and partially separating the inorganic salts from the resulting concentrated solution, wherein the membrane separation procedure employed is a continuous multi-step ultrafiltration procedure employing membranes with a molecular weight exclusion limit of about over 8000 Dalton and the partial separation of the inorganic salts is carried out by electrodialysis with the aid of membranes with a membrane permeability up to a molecular weight of about 300 Dalton.

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Patent Owner(s)

Patent OwnerAddress
SOLCO BASEL AG GELLERTSTRASE 18 CH-4052 BASEL A CORP OF SWITZERLANDNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Wittenberger, Udo Pratteln, CH 1 2

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