US Patent No: 4,599,230

Number of patents in Portfolio can not be more than 2000

Synthetic hepatitis B virus vaccine including both T cell and B cell determinants

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Abstract

Chemically synthesized polypeptides include amino acid residue sequences that substantially correspond to the amino acid residue sequences of T cell and B cell determinant portions of a natural, pathogen-related protein, in particular, a hepatitis B virus surface antigen (HBsAg). When administered to a host alone, as polymers or as carrier-bound conjugates, the polypeptides induce the proliferation of thymus-derived cells in hosts primed against hepatitis B virus.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
THE SCRIPPS RESEARCH INSTITUTELA JOLLA, CA889

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chisari, Frank V Del Mar, CA 2 164
Milich, David R Escondido, CA 18 343

Cited Art

Patent Info (Count) # Cites Year
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (2)
4,415,491 Synthetic vaccine peptide epitomes of hepatitis B surface antigen 35 1980
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INSTITUT PASTEUR (1)
4,428,941 Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby 54 1981

Patent Citation Ranking

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