Synthetic hepatitis B virus vaccine including both T cell and B cell determinants

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United States of America Patent

PATENT NO 4599230
SERIAL NO

06588122

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Chemically synthesized polypeptides include amino acid residue sequences that substantially correspond to the amino acid residue sequences of T cell and B cell determinant portions of a natural, pathogen-related protein, in particular, a hepatitis B virus surface antigen (HBsAg). When administered to a host alone, as polymers or as carrier-bound conjugates, the polypeptides induce the proliferation of thymus-derived cells in hosts primed against hepatitis B virus.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
The Scripps Research InstituteLA JOLLA, CA560

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chisari, Frank V Del Mar, CA 2 226
Milich, David R San Diego, CA 17 432

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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