US Patent No: 4,612,304

Number of patents in Portfolio can not be more than 2000

Antitumor formulation containing lipopolysaccharide with trehalose derivatives

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Abstract

Disclosed herein is an antitumor formulation, which contains an .alpha.,.alpha.-trehalose-6,6'-dicarboxylate, which is represented by the following general formula (I): ##STR1## wherein R means a C.sub.1 -C.sub.21 alkyl group, and a lipopolysaccharide. The antitumor formulation features low toxicity and high antitumor activities.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
SS PHARMACEUTICAL CO., LTD.TOKYO89

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fukushi, Kazue Hirosaki, JP 2 12

Cited Art

Patent Info (Count) # Cites Year
 
MITSUBISHI KASEI CORPORATION (1)
4,454,119 Therapeutic agents 5 1981
 
Other [Check patent profile for assignment information] (2)
4,307,229 6,6'-Diesters of trehalose and process for the synthesis thereof 17 1979
4,394,502 Immunotherapeutic agent for tumors comprising lipopolysaccharide as an active component 7 1981

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
SAWAI PHARMACEUTICAL CO., LTD. (2)
5,006,514 .alpha.,.alpha.-trehalose trimycolates and pharmaceutical compositions 3 1987
5,049,664 Trehalose derivatives 4 1989
 
Boehringer Mannheim GmbH (1)
5,473,058 Process and reagent for the specific determination of pancreatic .alpha.-amylase 0 1993
 
CPPD, INC., A CORP. OF IL (1)
4,761,401 Oligosaccharides 24 1986
 
Inflazyme Pharmaceuticals, Inc. (1)
5,399,683 Mirror amide cord factors and mirror thioester cord factors for diagnosis of tuberculosis 0 1993
 
MIZUNO, DEN'ICHI (1)
5,281,583 LPS-containing analgesics and veterinary analgesics 8 1991
 
SS Pharmaceutical Co., Ltd. (1)
4,814,436 Derivative of .alpha., .alpha.-trehalose and a process for preparing the same 23 1986