US Patent No: 4,612,331

Number of patents in Portfolio can not be more than 2000

Skin treatment composition

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Abstract

A cosmetically acceptable composition for topical application to human skin comprises from 0.1 to 20% by weight of a substituted 2-hydroxyoctanoic acid or 2-ketooctanoic acid or a mixture thereof, together with an amount of a special neutralizing agent sufficient to adjust the pH of the composition to a value of from 3 to 7. The special neutralizing agent is one having a cation whose ionic radius is at least 100 pm.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
LEVER BROTHERS COMPANYNEW YORK, NY1260

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barratt, Martin D Sharnbrook, GB2 3 166
Bowser, Paul A Merseyside, GB2 7 164
Durrant, James A Bedfont, GB2 5 156
George, Dieno Wirral, GB2 2 107
Hall, Keith J Wirral, GB2 2 107
Hill, John C Mesa, AZ 23 344
Lowry, Michael R Chester, GB 9 280
Prottey, Colin Bombay, IN 6 148

Cited Art

Patent Info (Count) # Cites Year
 
Lever Brothers Company (1)
4,507,319 Skin treatment composition 23 1983
 
Other [Check patent profile for assignment information] (2)
4,197,316 Treatment of dry skin 140 1978
4,234,599 Treatment of skin keratoses with .alpha.-hydroxy acids and related compounds 155 1978

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
TRISTRATA TECHNOLOGY, INC. (64)
5,385,938 Method of using glycolic acid for treating wrinkles 69 1992
5,665,776 Additives enhancing topical actions of therapeutic agents 30 1993
5,389,677 Method of treating wrinkles using glycalic acid 57 1993
5,470,880 Method of using citric acid for the treatment of wrinkles 38 1994
5,422,370 Method of using 2-hydroxypropanoic acid (lactic acid) for the treatment of wrinkles 36 1994
5,547,988 Alleviating signs of dermatological aging with glycolic acid, lactic acid or citric acid 42 1994
5,670,541 Method of treating wrinkles using gulonic acid or gulonolactone 1 1995
5,668,177 Method of treating wrinkles using tartaric acid 1 1995
5,591,774 Method of treating wrinkles using malic acid 3 1995
5,589,505 Method of treating wrinkles using quinic acid or quinolactone 7 1995
5,561,155 Method of treating wrinkles using galacturonic acid or galacturonolactone 1 1995
5,561,159 Method of treating wrinkles using tropic acid 1 1995
5,550,154 Method of treating wrinkles using glucuronic acid or glucuronolactone 1 1995
5,716,992 Method of using mucic acid or mucolactone for treating wrinkles 1 1995
5,677,339 Method of using mandelic acid for treating wrinkles 1 1995
5,677,340 Method of using gluconic acid or gluconolactone for treating wrinkles 3 1995
5,674,899 Method of using lactic acid for treating wrinkles 1 1995
5,674,903 Method of using citric acid for treating wrinkles 1 1995
5,670,542 Method of using glucuronic acid or glucronolactone for treating wrinkles 1 1995
5,670,543 Method of using pantoic acid or pantolactone for treating wrinkles 1 1995
5,656,665 Method of using quinic acid or quinolactone for treating wrinkles 6 1995
5,656,666 Method of using ribonic acid or ribonolactone for treating wrinkles 1 1995
5,654,340 Method of using gulonic acid or gulonolactone for treating wrinkles 2 1995
5,652,267 Method of using saccharic acid or saccharolactone for treating wrinkles 1 1995
5,650,436 Method of using galactonic acid or galactonolactone for treating wrinkles 1 1995
5,650,437 Method of using benzilic acid for treating wrinkles 1 1995
5,650,440 Method of using citramalic acid for treating wrinkles 1 1995
5,648,388 Method of using methyllactic acid for treating wrinkles 1 1995
5,648,391 Method of using galacturonic acid or galacturonolactone for treating wrinkles 1 1995
5,648,395 Method of using tartaric acid for treating wrinkles 2 1995
5,643,952 Method of using 2-phenyllactic acid for treating wrinkles 1 1995
5,643,953 Method of using 3-phenyllactic acid for treating wrinkles 1 1995
5,643,961 Method of using malic acid for treating wrinkles 2 1995
5,643,962 Method of using glucoleptonic acid for treating wrinkles 1 1995
5,643,963 Method of using isocitric acid for treating wrinkles 1 1995
5,612,376 Method of treating wrinkles using 3-phenyllactic acid 1 1995
5,599,843 Method of treating wrinkles using 2-phenyllactic acid 1 1995
5,583,156 Method of treating wrinkles using ribonic acid or ribonolactione 2 1995
5,580,902 Method of treating wrinkles using ethyl pyranate 4 1995
5,578,644 Method of treating wrinkles using isocitric acid 1 1995
5,574,067 Method of treating wrinkles using gluconic acid or gluconolactone 1 1995
5,571,841 Method of treating wrinkles using mandelic acid 2 1995
5,565,487 Method of treating wrinkles using galactonic acid or galactonolactone 2 1995
5,561,153 Method of treating wrinkles using mucic acid or mucolactone 1 1995
5,561,156 Method of treating wrinkles using methyllactic acid 1 1995
5,556,882 Methods of treating wrinkles using benzilic acid 1 1995
5,554,651 Method of treating wrinkles using citramalic acid 1 1995
5,550,158 Method of treating wrinkles using glucoheptonic acid 1 1995
5,942,250 Compositions and methods for enhancing the topical effects of sunscreen agents 7 1995
5,834,510 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 2 1995
5,690,967 Compositions for improved topical delivery of lactic acid 7 1995
5,691,378 Method for treating wrinkles using combinations of alpha hydroxyacids and/or alpha ketoacids 3 1995
5,686,489 Alpha hydroxyacid esters for skin aging 9 1995
5,684,044 Methods for improved topical delivery of lactic acid 3 1995
5,681,853 Methods for improved topical delivery of alpha hydroxyacids 5 1995
5,654,336 Methods of using glycolic acid for reversing or retarding the effect of aging on human facial skin 4 1995
5,571,837 Method of treating wrinkles using saccharic acid or saccharolactone 1 1995
5,561,158 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 12 1995
5,889,054 Method of using beta hydroxy acids for treating wrinkles 18 1997
5,962,526 Pharmaceutical compositions containing hydroxycarboxylic acids and/or ketocarboxylic acids and methods of using same 1 1997
5,856,357 Method for treating wrinkles using certain alpha hydroxyacids 4 1997
5,886,041 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use 9 1997
6,384,079 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 8 1999
6,191,167 Pharmaceutical compositions containing hydroxycarboxylic acid and/or ketocarboxylic acids and methods of using the same 10 1999
 
Chesebrough-Pond's USA Co., Division of Conopco, Inc. (3)
5,425,938 Polyamino salts of alpha-hydroxyacids, alpha-ketoacids and related compounds 14 1994
5,536,499 Cosmetic compositions for reducing or preventing signs of cellulite 10 1995
5,523,090 Skin treatment composition 32 1995
 
BASF CORPORATION (1)
8,231,887 Pesticidal compositions 0 2009
 
GOJO INDUSTRIES, INC. (1)
8,372,790 Antimicrobial hand wash 0 2011
 
SIGNUM BIOSCIENCES, INC. (1)
8,334,413 Topical compositions and methods for epithelial-related conditions 0 2010
 
The Procter & Gamble Company (1)
5,976,521 Anti-acne cosmetic compositions 2 1997
 
TRISTRATE, INCORPORATED (1)
5,827,882 Method of using ethyl pyruvate for treating wrinkles 3 1995
 
UNIVERSITY OF BRITISH COLUMBIA, THE, RESEARCH ADMINISTRATION (1)
5,175,190 Medium chain fatty acids of C8-10 for the treatment of skin lesions 8 1991
 
UPSHER-SMITH LABORATORIES, INC. (1)
8,013,017 Dermatological compositions and methods 0 2009
 
Other [Check patent profile for assignment information] (10)
5,621,006 Method for treating acne using benzilic acid 9 1995
5,561,157 Method for enhancing the therapeutic effect of a composition comprising hydroquinone and comprising same 18 1995
5,554,597 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 10 1995
5,554,652 Method of treating wrinkles using alpha hydroxyacids, alpha ketoacids and a sunscreen agent 4 1995
5,554,654 Method for enhancing the therapeutic effect of an anti-acne agent 29 1995
6,335,023 Oligosaccharide aldonic acids and their topical use 26 2000
6,740,327 Oligosaccharide aldonic acids and their topical use 7 2001
7,452,545 Oligosaccharide aldonic acids and their topical use 0 2004
7,767,452 Tissue treatments with adipocyte cells 8 2007
7,799,325 Removal of hypertrophic scars 0 2007