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Abstract

The invention concerns novel anti-arrhythmic amino-alcohol derivatives, characterized by the general formula (1) ##STR1## or pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.2 and R.sub.3 each independently represent hydrogen, alkyl having 1-6 carbon atoms, alkoxy having 1-6 carbon atoms, acyloxy having 1-6 carbon atoms, hydroxy, halogen or optionally alkyl-substituted amino; R.sub.4 represents hydrogen, hydroxy or alkyl having 1-6 carbon atoms, R.sub.5 represents hydrogen or alkyl having 1-6 carbon atoms, R.sub.6 represents hydrogen, acyl having 1-18 carbon atoms or alkyl having 1-6 carbon atoms, R.sub.7 and R.sub.8 each independently represent hydrogen or alkyl having 1-6 carbon atoms, X represents a direct bond or an oxygen atom, and n and m each independently are integers having a value of 1 or 2, whereby the sum of n and m is 2 or 3.

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First Claim