Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same

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United States of America Patent

PATENT NO 4623627
SERIAL NO

06524596

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Abstract

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Monoclonal antibodies having conformation-dependent specificity for native dsDNA, as exemplified by the IgM antibody produced by murine hybridoma ATCC No HB 8329. These antibodies are used to detect DNA duplex formation in DNA hybridization tests.

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Patent Owner(s)

Patent OwnerAddress
CHIRON CORPORATION4650 HORTON STREET EMERYVILLE CALIFORNIA 94608 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cohen, Stanley N Portola Valley, CA 51 1002
Huang, Chun-Ming Cupertino, CA 120 584

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