PAF-antagonistic diazepines, methods of use
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United States of America Patent
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-
Nov 18, 1986
Grant Date -
N/A
app pub date -
Oct 1, 1985
filing date -
Oct 1, 1984
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention discloses a method of treating an individual having a disorder responsive to PAF-antagonist activity by treating the individual with a compound of formula I. ##STR1## wherein A is an anellated and optionally substituted benzene or 5- or 6-membered heterocyclic ring; R.sub.5 and Z are each independently hydrogen or an optionally substituted C.sub.1 -C.sub.8 alkyl, alkenyl or alkynyl; R.sub.6 is an optionally substituted phenyl, or is thienyl or .alpha.-pyridyl; Y is ##STR2## and nontoxic, pharmaceutically acceptable acid addition salts thereof.
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