High yield process for preparing beta-lactam antibiotics having a high purity degree

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United States of America Patent

PATENT NO 4625021
SERIAL NO

06740251

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Abstract

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A high yield process for preparing beta-lactam antibiotics having a high purity degree, in particular derivatives of the cephalosporanic and penicillanic acids, of the formula: ##STR1## by condensation of the compounds ##STR2## where X.dbd.H --OCH.sub.3 (suitably blocked), with a chloride of the formula ##STR3## wherein R.dbd.H, OH in which said condensation is carried out in the presence of a nicotinic or isonicotinic base.

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Patent Owner(s)

Patent OwnerAddress
ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S P A04011 APRILIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Farina, Paolo Milan, IT 5 2
Marotta, Vittorio Milan, IT 2 1
Valcavi, Umberto Milan, IT 4 7

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