Erodible matrix for sustained release bioactive composition
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United States of America Patent
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-
Dec 16, 1986
Grant Date -
N/A
app pub date -
Jul 23, 1984
filing date -
Jul 23, 1984
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of 5 to 95% by weight of a polyethylene glycol having a molecular weight of from about 1000 to about 20,000, and 95 to 5% by weight of an erosion rate modifier which is an amphiphilic compound insoluble in the aqueous liquid. Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding.
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