Heparin compositions freed of mineral salts, particularly oxalates, and process for obtaining same
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United States of America Patent
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Mar 24, 1987
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N/A
app pub date -
Dec 22, 1982
filing date -
Aug 8, 1977
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Expired
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Abstract
This invention relates to oxalate-free preparations of heparin, particularly in the form of calcium salts of heparin, which can be used for the preparation of injectable solutions of heparin which have long storage life. The invention is also directed to a process for freeing heparin from its oxalate content, such as by fractional precipitations by alcohol in the presence of adjusted amounts of mineral salt, until the heparin precipitated contains less than about 70 ppm of oxalate but may contain less than about 30 ppm, preferably even less than 20 ppm.
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