Method for the production of acemetacin
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United States of America Patent
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Mar 24, 1987
Issued Date -
N/A
app pub date -
Oct 16, 1984
filing date -
Dec 28, 1981
priority date (Note) -
Expired
status (Latency Note)
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Abstract
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester as known per se is obtainable by a novel and more simple method comprising mild acid hydrolysis of 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetoxyacetic tetrahydropyran-2-yl ester. The final product is a valuable drug having antiinflammatory activity.
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