Flavene and thioflavene derivatives

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United States of America Patent

PATENT NO 4665202
SERIAL NO

06644006

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to pharmaceutical preparations containing compounds of formula I ##STR1## in which X.sub.1 and X.sub.2, independently of each other, represent hydrogen, halogen, unsubstituted or substituted amino or a quaternary ammonium salt; etherified or esterified hydroxy; free, etherified, esterified or oxidized mercapto; nitro; functionally modified formyl; free or functionally modified carboxyl; acyl; an unsubstituted or substituted hydrocarbon radical, or an unsubstituted or substituted heterocyclic radical; with the proviso that at least one of the radicals X.sub.1 and X.sub.2 is bonded by a carbon atom to the ring system and with the proviso that X.sub.1 and X.sub.2 cannot be together halogen and formyl; in which Y represents oxygen, sulfur, sulfinyl or sulfonyl but must be sulfur, sulfinyl or sulfonyl, if X.sub.1 is hydrogen and X.sub.2 is formyl, and the rings A and B are each unsubstituted or substituted; or pharmaceutically acceptable salts of such compounds that contain a salt-forming group, and to novel compounds of formula I. The compounds are useful e.g. for the treatment of diseases of the respiratory tract and of liver diseases. The are prepared by methods known per se.

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Patent Owner(s)

Patent OwnerAddress
ZYMA SAROUTE DE L'ETRAZ 1260 NYON

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Narbel, Philippe M Prangins, CH 2 17
Rimbault, Christian G Grand-Lancy, CH 5 38

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