Preparation of biodegradable microcapsules based on serum albumin

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United States of America Patent

PATENT NO 4666641
SERIAL NO

06741190

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Abstract

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The present invention relates to biodegradable microcapsules based on serum albumin, the preparation thereof and the application thereof to the release of drugs in situ. A feature of the microcapsules according to the present invention is that their wall consists of serum albumin, a portion of which is crosslinked by interfacial polymerization with the aid of an acylating bifunctional reagent, and the other, non-crosslinked portion of which is denatured by means of an alcohol.

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Patent Owner(s)

  • UNIVERSITE PARIS-SUD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benita, Simon Puteaux, FR 29 522
Fickat, Rene Reims, FR 1 66
Puisieux, Francis Maisons-Alfort, FR 10 616

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