Polypeptide marker for Alzheimer's disease and its use for diagnosis

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United States of America Patent

PATENT NO 4666829
SERIAL NO

06734660

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Abstract

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A novel polypeptide, Alzheimer's Amyloid Polypeptide (AAP), is provided in substantially purified form which is isolated from amyloid deposits in patients with Alzheimer's Disease. The polypeptide has the following amino acid sequence: ##STR1## The polypeptide, or fragments thereof, may be used to produce antibodies useful in a diagnostic test for Alzheimer's Disease. Nucleotide probes corresponding to portions of the polypeptide are also useful for diagnostic purposes.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF CALIFORNIA THE300 LAKESIDE DRIVE 22ND FLOOR OAKLAND CA 94612 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Glenner, George G La Jolla, CA 1 315
Wong, Caine W Cardiff, CA 1 315

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