2-(4-Phenylpiperazinylethyl) anilines

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United States of America Patent

PATENT NO 4668681
SERIAL NO

06843915

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Abstract

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This invention relates to 2-(4-phenylpiperazinylethyl)anilines, to methods for preparing them and to their uses in medical therapy. These compounds have the following general formula ##STR1## wherein R.sub.1 represents one or more substituents selected from the group consisting of H, CH.sub.3, CF.sub.3, F, Cl, and OCH.sub.3 ; R.sub.2 and R.sub.3, which may be the same or different, and are selected from the group consisting of H and (C.sub.1 -C.sub.4) alkoxy, or R.sub.2 and R.sub.3 taken together can form a chain selected from the group consisting of --O-- (CH.sub.2).sub.n --O--, wherein n=1 or 2 and --O--CH.sub.2 --O--CH.sub.2 with the proviso that R.sub.1 is not meta CF.sub.3 when R.sub.2 =R.sub.3 =H, and pharmaceutically non-toxic salts thereof. The compounds of this invention are useful in the treatment of allergic and anaphylatic conditions and motion sickness.

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Patent Owner(s)

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SOCIETE CORTAIL S A7 RUE DE L'ARMORIQUE 75015 PARIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Creuzet, Marie-H/e/ l/e/ ne Bordeaux, FR 1 1
Feniou, Claude Pessac, FR 17 61
Guichard, Francoise Bordeaux, FR 7 36
Pontagnier, Henri Pessac, FR 15 68
Prat, Gis/e/ le Talence, FR 1 1

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