US Patent No: 4,671,288

Number of patents in Portfolio can not be more than 2000

Electrochemical cell sensor for continuous short-term use in tissues and blood

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Abstract

An electrochemical cell sensor for monitoring oxidizable enzyme substrates in biological fluids situated in a housing and suitable for implantation in the body, including at least one oxygen or hydrogen peroxide sensing electrode containing a suitable oxidase enzyme, a reference electrode, and a counter electrode all in communication with biological fluids through one or more openings in the walls of the housing.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
THE REGENTS OF THE UNIVERSITY OF CALIFORNIAOAKLAND, CA7204

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gough, David A Cardiff, CA 20 2782

Cited Art

Patent Info (Count) # Cites Year
 
DR. EDUARD FRESENIUS CHEMISCH-PHARMAZEUTISCHE INDUSTRIE KG, APPARATEBAU KG (1)
4,197,852 Catheter electrode for electrochemical analysis 34 1978
 
MEDISENSE, INC. (1)
4,545,382 Sensor for components of a liquid mixture 460 1982
 
PHOTOVOLT CORPORATION (1)
4,419,210 Polarographic electrode 4 1982
 
SIEMENS AKTIENGESELLSCHAFT (1)
4,366,033 Method for determining the concentration of sugar using an electrocatalytic sugar sensor 170 1979

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
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6,616,819 Small volume in vitro analyte sensor and methods 324 1999
6,551,494 Small volume in vitro analyte sensor 297 2000
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6,654,625 Mass transport limited in vivo analyte sensor 313 2000
6,591,125 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 422 2000
6,329,161 Subcutaneous glucose electrode 451 2000
6,942,518 Small volume in vitro analyte sensor and methods 218 2001
6,749,740 Small volume in vitro analyte sensor and methods 199 2001
7,003,340 Electrochemical analyte sensor 175 2002
7,058,437 Methods of determining concentration of glucose 186 2003
7,550,069 Small volume in vitro analyte sensor 2 2003
7,225,535 Method of manufacturing electrochemical sensors 180 2003
7,563,350 Small volume in vitro analyte sensor 4 2003
7,381,184 Sensor inserter assembly 40 2003
6,975,893 Mass transport limited in vivo analyte sensor 100 2003
7,811,231 Continuous glucose monitoring system and methods of use 14 2003
8,066,639 Glucose measuring device for use in personal area network 0 2004
8,112,240 Method and apparatus for providing leak detection in data monitoring and management systems 0 2005
7,976,778 Blood glucose tracking apparatus 2 2005
7,462,264 Subcutaneous glucose electrode 1 2005
7,721,412 Method of making an electrochemical sensor 6 2005
7,731,657 Analyte sensor introducer and methods of use 0 2005
7,883,464 Integrated transmitter unit and sensor introducer mechanism and methods of use 2 2005
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7,736,310 On-body medical device securement 2 2006
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7,885,698 Method and system for providing continuous calibration of implantable analyte sensors 0 2006
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8,123,686 Method and apparatus for providing rolling data in communication systems 0 2007
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7,768,386 Method and apparatus for providing data processing and control in a medical communication system 10 2007
8,029,442 Sensor inserter assembly 0 2007
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7,988,845 Integrated lancing and measurement device and analyte measuring methods 0 2008
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8,377,031 Closed loop control system with safety parameters and methods 0 2008
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8,219,173 Optimizing analyte sensor calibration 0 2008
8,409,093 Assessing measures of glycemic variability 0 2008
8,374,668 Analyte sensor with lag compensation 0 2008
8,216,138 Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration 1 2008
8,414,749 Subcutaneous glucose electrode 0 2008
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8,103,456 Method and device for early signal attenuation detection using blood glucose measurements 2 2009
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7,948,369 Method and apparatus for providing dynamic multi-stage signal amplification in a medical device 3 2010
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8,414,750 Subcutaneous glucose electrode 0 2010
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8,362,904 Analyte monitoring system and methods 0 2011
8,149,103 Method and apparatus for providing dynamic multi-stage amplification in a medical device 1 2011
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7,226,978 Techniques to improve polyurethane membranes for implantable glucose sensors 204 2002
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7,192,450 Porous membranes for use with implantable devices 255 2003
7,134,999 Optimized sensor geometry for an implantable glucose sensor 329 2003
7,110,803 Device and method for determining analyte levels 238 2003
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8,050,731 Techniques to improve polyurethane membranes for implantable glucose sensors 2 2005
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7,920,906 System and methods for processing analyte sensor data for sensor calibration 11 2006
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8,251,906 Signal processing for continuous analyte sensor 1 2009
8,064,977 Silicone based membranes for use in implantable glucose sensors 0 2009
7,976,492 Integrated delivery device for continuous glucose sensor 3 2009
8,290,561 Signal processing for continuous analyte sensor 0 2009
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8,265,725 Signal processing for continuous analyte sensor 1 2009
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8,150,488 Systems and methods for replacing signal artifacts in a glucose sensor data stream 5 2009
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7,792,562 Device and method for determining analyte levels 54 2009
8,255,032 Oxygen enhancing membrane systems for implantable devices 0 2010
8,053,018 Techniques to improve polyurethane membranes for implantable glucose sensors 2 2010
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8,005,524 Signal processing for continuous analyte sensor 21 2010
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7,974,672 Device and method for determining analyte levels 10 2010
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8,290,562 System and methods for processing analyte sensor data 2 2010
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8,073,520 Systems and methods for replacing signal artifacts in a glucose sensor data stream 6 2010
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8,311,749 Transcutaneous analyte sensor 0 2011
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7,344,500 Sensing system with auxiliary display 65 2004
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7,552,522 Method of making a sensing apparatus 0 2004
7,303,543 Medication infusion set 19 2004
7,704,229 Insertion device 1 2005
7,602,310 Telemetered characteristic monitor system and method of using the same 38 2005
7,324,012 Telemetered characteristic monitor system and method of using the same 93 2005
7,713,240 Modular external infusion device 5 2005
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8,386,042 Omnidirectional accelerometer device and medical device incorporating same 0 2009
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8,192,395 System for providing blood glucose measurements to an infusion device 1 2010
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8,065,096 Method and apparatus for detecting occlusions in an ambulatory infusion pump 0 2010
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8,267,893 Method and apparatus for detecting occlusions in an ambulatory infusion pump 0 2011
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6,952,604 Minimally-invasive system and method for monitoring analyte levels 249 2001
6,904,301 Micro-invasive method for painless detection of analytes in extracellular space 148 2002
7,409,238 Micro-invasive method for painless detection of analytes in extracellular space 0 2005
 
ISENSE CORPORATION (4)
6,695,860 Transcutaneous sensor insertion device 195 2000
7,529,574 Method of constructing a biosensor 0 2003
7,120,483 Methods for analyte sensing and measurement 110 2003
RE43187 Methods for analyte sensing and measurement 0 2008
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (4)
5,985,129 Method for increasing the service life of an implantable sensor 154 1992
6,592,746 Sensor probe for determining hydrogen peroxide concentration and method of use thereof 13 2000
7,248,912 Tissue implantable sensors for measurement of blood solutes 26 2003
7,336,984 Membrane and electrode structure for implantable sensor 16 2003
 
VALERITAS LLC (4)
6,743,211 Devices and methods for enhanced microneedle penetration of biological barriers 222 1999
7,344,499 Microneedle device for extraction and sensing of bodily fluids 118 1999
6,611,707 Microneedle drug delivery device 67 1999
7,226,439 Microneedle drug delivery device 10 2003
 
E. HELLER & COMPANY, INC. (3)
6,143,164 Small volume in vitro analyte sensor 474 1998
6,120,676 Method of using a small volume in vitro analyte sensor 535 1999
6,576,101 Small volume in vitro analyte sensor 298 1999
 
BAYER HEALTHCARE LLC (2)
8,425,757 Gated amperometry 0 2007
8,404,100 Gated voltammetry 0 2008
 
LIFESCAN, INC. (2)
6,875,613 Biological fluid constituent sampling and measurement devices and methods 79 2001
7,361,307 Biological fluid constituent sampling and measurement devices 56 2004
 
MINIMED INC. (2)
6,340,421 Microelectrogravimetric method for plating a biosensor 57 2000
6,811,659 Microelectrogravimetrically plated biosensors and apparatus for producing same 139 2001
 
VALERITAS, INC. (2)
7,027,478 Microneedle array systems 47 2001
8,361,037 Microneedles, microneedle arrays, and systems and methods relating to same 0 2002
 
A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (1)
5,176,632 Wearable artificial pancreas 52 1990
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (1)
7,532,920 Guidewire with optical fiber 19 2001
 
ADVANCED BIONICS, LLC (1)
6,181,969 Programmable current output stimulus stage for implantable device 118 1999
 
ARROWHEAD CENTER, INC. (1)
6,893,552 Microsensors for glucose and insulin monitoring 170 2001
 
AVANIR PHARMACEUTICALS (1)
7,236,890 Transcutaneous analyte sensor 0 2006
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
6,284,478 Subcutaneous glucose electrode 371 1996
 
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (1)
5,611,900 Microbiosensor used in-situ 182 1995
 
CHIRON DIAGNOSTICS CORPORATION (1)
5,773,270 Three-layered membrane for use in an electrochemical sensor system 146 1994
 
GE HEALTHCARE UK LIMITED (1)
7,905,996 Interface patch clamping 0 2003
 
GEORGIA TECH RESEARCH CORPORATION (1)
8,257,324 Microneedle drug delivery device 0 2007
 
INSTITUT FUER DIABETES-TECHNOLOGIE GEMEINNUETZIGE FORSCHUNGS-UND ENTWICKLUNGSGESELLSCHAFT MBH AN DER UNIVERSITAET ULM (1)
5,640,954 Method and apparatus for continuously monitoring the concentration of a metabolyte 197 1995
 
NOVO NORDISK A/S (1)
5,680,858 Method and apparatus for in vivo determination of the concentration in a body fluid of metabolically significant substances 232 1995
 
OXYGEN BIOTHERAPEUTICS, INC. (1)
5,914,026 Implantable sensor employing an auxiliary electrode 166 1997
 
PHARMACONTROL CORPORATION (1)
4,750,496 Method and apparatus for measuring blood glucose concentration 212 1987
 
TEKNEKRON CORPORATION (1)
5,304,293 Microsensors for gaseous and vaporous species 46 1992
 
TERUMO KABUSHIKI KAISHA (1)
4,927,516 Enzyme sensor 289 1987
 
UNIVERSITY OF KANSAS (1)
5,165,407 Implantable glucose sensor 448 1991
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (3)
8,444,560 Method and apparatus for providing data processing and control in a medical communication system 0 2008
8,442,610 System and methods for processing analyte sensor data 0 2008
8,447,376 Analyte sensor 0 2008