Fractionation/purification of plasma by ion exchange chromatography
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United States of America Patent
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Jun 23, 1987
Grant Date -
N/A
app pub date -
Apr 2, 1984
filing date -
Apr 1, 1983
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The plasma proteins contained in a plasma solution thereof are chromatographically fractioned, e.g., to obtain a high purity therapeutic grade albumin product, by successively contacting said plasma solution with at least one anion exchanger and at least one cation exchanger in fixed bed chromatography columns, the contact and exchange medium of chromatography therein also comprising a plurality of at least partially hydrophobic support particulates and a plurality of hydrophilic ion exchanger support particulates.
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