Visualization polymers and their application to diagnostic medicine

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United States of America Patent

PATENT NO 4687732
SERIAL NO

06503298

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for detecting a minute quantity of an inorganic or organic target molecule by combining it with a composition of a detecting agent for the target molecule which carries, by direct or indirect means, a visualization polymer. The visualization polymer is composed of multiple units of a visualization monomer which are covalently linked together directly or indirectly covalently linked together by coupling agents which bond to chemical groups of the monomer. The monomer may be an enzyme, a tagged polypeptide, a tagged polyol, a tagged polyolefin or a tagged carbohydrate. The detecting agent may be an antibody, an enzyme, a lectin, strand of a DNA receptor protein, avidin, streptavidin and the like. The visualization polymer produces a high degree of amplification for the detection of the target molecule.

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YALE UNIVERSITY A STATE OF CONNECTICUTNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brigati, David J Hershey, PA 9 634
Leary, Jeffry J East Haven, CT 2 140
Ward, David C Guilford, CT 30 2160

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