Magnetic carbohydrate particles as carriers for affinity separation purposes
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United States of America Patent
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Aug 18, 1987
Grant Date -
N/A
app pub date -
Nov 7, 1983
filing date -
Mar 29, 1982
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Magnetically responsive spheres having an average diameter less than 1,000 nm are prepared by dissolving a carbohydrate polymer in a polar solvent, suspending magnetic material in the dissolved carbohydrate, emulsifying the suspension with an emulsion liquid to form an emulsion containing droplets of the suspension and then contacting the emulsion with a crystallizing liquid capable of crystallizing the carbohydrate polymer. The resulting spheres may be bonded with a bioabsorptive material and can be employed in processes such as cell separation, affinity purification or immunochemical assays.
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