Method of producing monoclonal anti-idiotype antibody
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United States of America Patent
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Oct 13, 1987
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N/A
app pub date -
Sep 25, 1984
filing date -
Sep 25, 1984
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Abstract
A method for determining the presence of an antigen in a liquid sample. The method includes incubating the sample with an antibody which specifically binds an epitope on the antigen in the presence of a given quantity of an anti-idiotype antibody which specifically binds an epitope on the hypervariable region of the antibody. Also, a method of producing a monoclonal anti-idiotype antibody by fusing lymphocytes from an animal in which a tumor capable of secreting idiotype antibodies has been grown, with myeloma cells.
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