Modified signal peptides
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United States of America Patent
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Dec 8, 1987
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N/A
app pub date -
Mar 9, 1983
filing date -
Mar 9, 1983
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Expired
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Abstract
The invention discloses a method for producing modified signal peptides sequences derived from wild-type signal peptide sequences of the type that are capable of forming membrane-bound lipoproteins. Modified signal peptide sequences produced by the method of the invention are useful for increasing the secretion of heterologous gene products produced by transformed host organisms. The invention further discloses a method for producing recombinant DNA sequences in vivo.
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