US Patent No: 4,711,902

Number of patents in Portfolio can not be more than 2000

Medicament formulation

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ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

A medicament formulation of intravenous injection comprising a medicinally active compound, a lipid phase, an emulsifier and water, the lipid phase being present in up to about 30% by weight, the emulsifier being present in about 0.1 to 10% by weight, and water being present up to 100%, the lipid phase containing up to about 50% by weight of a sparingly soluble medicinally active compound, and consisting essentially of (a) at least one ester principally of at least one medium chain-length fatty acid, or (b) a mixture of at least one ester principally of at least one medium chain-length fatty acid with at least one vegetable or animal oil, the mixture containing at least 10% by weight of the ester principally of the medium chain-length fatty acid, or (c) at least one ester principally of at least one medium chain-length fatty acid, at least one vegetable or animal oil, or a mixture thereof, in combination with 0.3 to 200% by weight of benzyl alcohol based on the content of lipid or oil. A greater amount of medicinal agent can be administered in a reduced total volume of injectable liquid.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BAYER AKTIENGESELLSCHAFTLEVERKUSEN9293

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Serno, Peter Bergisch Gladbach, DE 28 159

Cited Art

Patent Info (Count) # Cites Year
 
ASTRA AKTIEBOLAG (1)
4,264,611 2,6-Dimethyl-4-2,3-disubstituted phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid-3,5-asymmetric diesters having hypotensive properties, as well as method for treating hypertensive conditions and pharmaceutical preparations containing same 22 1979
 
Bayer Aktiengesellschaft (1)
4,237,137 Sila-substituted 1,4-dihydropyridine derivatives and their medicinal use 10 1979

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
EKR THERAPEUTICS, INC. (5)
5,164,405 Nicardipine pharmaceutical composition for parenteral administration 7 1990
7,612,102 Pre-mixed, ready-to-use pharmaceutical compositions 3 2007
7,659,290 Methods of preparing pre-mixed, ready-to-use pharmaceutical compositions 3 2009
7,659,291 Methods of treatment with pre-mixed, ready-to-use pharmaceutical compositions 3 2009
8,455,524 Methods of treatment with pre-mixed, ready-to-use pharmaceutical compositions 0 2010
 
THERAVANCE, INC. (5)
6,887,866 Short-acting sedative hypnotic agents for anesthesia and sedation 4 2003
7,790,766 Pharmaceutical compositions of short-acting sedative hypnotic agent 0 2004
7,514,425 Short-acting sedative hypnotic agents for anesthesia and sedation 3 2006
7,939,689 Short-acting sedative hypnotic agents for anesthesia and sedation 0 2009
7,981,931 Pharmaceutical compositions of short-acting sedative hypnotic agent 0 2009
 
WATSON LABORATORIES, INC. (5)
5,858,401 Pharmaceutical composition for cyclosporines 42 1997
7,070,802 Pharmaceutical compositions for lipophilic drugs 3 2001
7,988,995 Pharmaceutical compositions for lipophilic drugs 0 2002
8,119,157 Pharmaceutical compositions for lipophilic drugs 0 2006
7,799,340 Pharmaceutical compositions for lipophilic drugs 0 2007
 
ATHENA NEUROSCIENCES, INC. (4)
5,444,041 Convertible microemulsion formulations 86 1992
5,646,109 Convertible microemulsion formulations 22 1995
5,633,226 Convertible microemulsion formulations 25 1995
5,688,761 Convertible microemulsion formulations 21 1995
 
PAUL ROYALTY FUND, L.P. (2)
7,097,849 Injectable aqueous dispersions of propofol 0 1999
7,041,705 Injectable aqueous dispersions of propofol 3 2001
 
ABBOTT LABORATORIES (1)
5,134,130 Lipid emulsion for treating aids 4 1991
 
ASTRAZENECA AB (1)
5,739,152 Pharmaceutical emulsion 9 1994
 
ATRIUM MEDICAL CORPORATION (1)
8,460,693 Intraluminal device with a coating containing synthetic fish oil and a therapeutic agent 0 2002
 
Lion Corporation (1)
5,094,840 Foamable dentifrice composition 16 1990
 
LIPOCINE INC. (1)
6,720,001 Emulsion compositions for polyfunctional active ingredients 49 1999
 
NIPPON SHINYAKU CO., LTD. (1)
5,534,502 Process for producing fat emulsion 6 1995
 
NOVARTIS AG (1)
4,990,337 Cyclosporin formulations of mono or diglyceride fatty acid 76 1990
 
PDT, Inc. (1)
5,616,342 Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof 30 1995
 
PLIVA, INC. (1)
7,452,552 Pharmaceutical compositions for lipophilic drugs 0 2007
 
POLICHEM S.A. (1)
6,979,672 Cyclosporin-based pharmaceutical compositions 0 2002
 
RTP PHARMA INC. (1)
6,979,456 Anticancer compositions 12 1999
 
Other [Check patent profile for assignment information] (3)
4,904,699 Nifedipine concentrate stabilized against the influence of light and a process for its preparation 34 1987
8,466,178 Pre-mixed, ready-to-use pharmaceutical compositions 0 2009
8,466,179 Methods of preparing pre-mixed, ready-to-use pharmaceutical compositions 0 2010