Quadroma cells and trioma cells and methods for the production of same
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United States of America Patent
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Dec 22, 1987
Issued Date -
N/A
app pub date -
Jun 18, 1984
filing date -
Jul 1, 1981
priority date (Note) -
Expired
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Abstract
Antibodies having binding affinity for two desired antigens, hereinafter 'recombinant monoclonal antibodies'; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.
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