Separation of citric acid from fermentation broth with a neutral polymeric adsorbent
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United States of America Patent
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Jan 19, 1988
Grant Date -
N/A
app pub date -
Dec 18, 1986
filing date -
Dec 18, 1986
priority date (Note) -
Expired
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Abstract
Citric acid is separated from a fermentation broth by using an adsorbent comprising a neutral, noniogenic, macroreticular, water-insoluble, crosslinked styrene-poly(vinyl)benzene and a desorbent comprising water and, optionally, acetone with the water. The pH of the feed is adjusted and maintained below the first ionization constant (pKa.sub.1) of citric acid to maintain selectivity.
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