Method for controlling bleeding
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United States of America Patent
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-
Jan 26, 1988
Issued Date -
N/A
app pub date -
Aug 9, 1985
filing date -
Jun 27, 1983
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Factor VIII:C deficiency in a hemophilic mammal may be bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture are critical as too little Xa has no effect while too much is toxic (thrombogenic). Infusion of the phosphilipid-Factor Xa mixture into normal mammals enhances the natural clotting rate and provides a method for rapidly controlling bleeding in emergency situations.
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