N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans having improved oral bioavailability, pharmaceutical compositions, and processes

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United States of America Patent

PATENT NO 4722928
SERIAL NO

06803222

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Abstract

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N-oxide prodrug derivatives of 3-hydroxy morphinan and partial morphinan analgesics, agonist-antagonists, and narcotic antagonists are useful therapeutic entities which provide enhanced bioavailability of 3-hydroxy morphinans and partial morphinans from orally administered dosage forms.

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Patent Owner(s)

Patent OwnerAddress
DU PONT MERCK PHARMACEUTICAL COMPANYNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boswell, George A Wilmington, DE 14 222
Myers, Melvyn J Wilmington, DE 10 175

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