Granular delayed-release form of pharmaceutically active substances
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United States of America Patent
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-
Mar 1, 1988
Grant Date -
N/A
app pub date -
Jul 23, 1986
filing date -
Jul 31, 1985
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A granular delayed-release form of pharmaceutically active substances, which is prepared by coating a granulated or crystalline pharmaceutically active substance, or mixtures thereof, with a coating material mixture consisting essentially of a homogeneous mixture of a poly(H+meth)-acrylic acid-(methyl+ethyl)ester which is insoluble but dispersible in water and an ethyl cellulose which is insoluble but dispersible in water in the weight ratio of 20:1 to 1:5, is presented, which is characterized by the fact that the coated granules are heated for at least 5 minutes at elevated temperatures ranging from between 50.degree. to 120.degree. C.
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