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Abstract

An improvement in NMR imaging techniques is disclosed, whereby the image is 'shadowed' to intensify and contrast the image generated by the NMR sensitive nuclei, as a consequence of the introduction to the examined locus, e.g., human tissue of ferromagnetic, diamagnetic or paramagnetic particles. The intensified and clarified image is itself diagnostically valuable, in accordance with art recognized methods but also provides an improved information base for establishing and controlling treatment modes, especially in determining spatial density and distribution of particles by comparing standard and enhanced images. According to a preferred embodiment, metabolizable particles are employed, whereby the change and rate of change with metabolic time can be imaged, compared, and correlated with various metabolic diseases or malignant states.

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First Claim