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Abstract

Separation of particles types from a mixed population of particles in a liquid is obtained in an ultrasonic wave produced by interference between the outputs from spaced ultrasonic sources (115,118). One or more selected particle types may be separated by displacement axially along the standing wave or may be carried transversely through the standing wave or by combining both methods. The described separation can be achieved by control of flow of the liquid or giving the standing wave a drift, or by controlling the intensity or the frequency of the standing wave or by any combination of these factors. The preferred ultrasonic frequency range is between 100 kHz and 100 MHz. The process is particularly suitable for the separation of biological particles, from macromolecules to plant cells.

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First Claim