Fluoro coumarins as antilymphoedema agents

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United States of America Patent

PATENT NO 4749798
SERIAL NO

06808555

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A compound of the formula ##STR1## wherein hydrogen, fluorine, chlorine or bromine; B is fluorine, or when A is fluorine B may be hydrogen; R is hydrogen, C.sub.1 -C.sub.8 branched or unbranched alkyl, CH.sub.2 BR, CH.sub.2 Cl or substituted or unsubstituted phenyl; X is hydrogen, chlorine or bromine; one of R.sub.1 and R.sub.2 is hydrogen and the other is hydroxy or C.sub.1 -C.sub.7 branched or unbranched alkoxy unsubstituted or substituted by a dialkyl amino group, or R.sub.1 and R.sub.2, taken together with the carbon atom to which they are linked, form the group ##STR2## with the proviso that, when R and X are both hydrogen, ##STR3## is a ##STR4## group, and B is fluorine and A is hydrogen is useful as antilimphoedema agent.

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Patent Owner(s)

Patent OwnerAddress
BOEHRINGER BIOCHEMIA ROBIN SPAVIA S UGUZZONE 5 A CORP OF ITALY 20126 MILAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cipolla, PierVitto Lodi, IT 2 15
Gandolfi, Carmelo A Milan, IT 26 64
Spinelli, Silvano Milan, IT 41 182
Tofanetti, Odoardo Milan, IT 19 65
Tognella, Sergio Milan, IT 28 177

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