Thrombin aerosol

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 4752466
SERIAL NO

07091165

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Abstract

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A process is disclosed for delivery thrombin in dry powdered form from an aerosol container by first lyophilizing an aqueous solution of thrombin and a thrombin-compatible synthetic polymer e.g. polyvinyl pyrrolidone, placing the lyophilized cake in a pressure bottle by crimping on a valve stem and top, filling liquified chlorofluoroalkane-containing aerosol propellant into the bottle, and actuating the valve to dispense in dry-finely divided powdered form a mixture of thrombin and polyvinyl pyrrolidone, which powdered thrombin is for use in controlling bleeding during surgery.

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Patent Owner(s)

Patent OwnerAddress
JOHNSON & JOHNSON MEDICAL INC2500 ARBROOK BOULEVARD ARLINGTON NJ 76004

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Saferstein, Lowell Edison, NJ 15 1007
Wolf, Stephen J Manville, NJ 14 933

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