Iodophor-containing suppository
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United States of America Patent
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-
Jul 5, 1988
Grant Date -
N/A
app pub date -
Jul 30, 1986
filing date -
Aug 17, 1985
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Iodophor-containing suppositories are provided with improved rate of iodine release from the suppository. The suppository composition comprises an iodophor, a water soluble suppository base, at least one water soluble sugar having a molecular weight of between about 90 and 550, and water in an amount of at least about 30% by weight. The molecular weight of the sugar is preferably between about 150 and 370. The preferred iodophors are providone iodine and polydextrose iodine. The preferred suppository bases are gelling polysaccharides and the preferred sugars are monosaccharides, disaccharides and sugar alcohols. The rate of iodine release is improved because of the high concentration of water together with the presence of the low molecular weight sugar.
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